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Forms
- Use the full page Analysis Request Form for ordering Toxicology Surveys and
Therapeutic Drug Monitoring.
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Use the half page
request form or the chain of custody form for ordering Urine Drugs of Abuse
testing.
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For supplies such as forms, containers, bags, etc., contact the lab.
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For STAT or
routine pick-ups, please call the lab (215) 322-9210.
Group
Tests
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Panels-
Small groups of drugs pharmacologically related, reported qualitatively.
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Surveys-
Drug and toxic substances screens.
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Profiles-
Groups covered with quantitative results.
Concentration units used
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Concentration
Unit |
Abbreviation |
Equivalent Units |
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grams/Liter |
g/L |
mg/mL or parts
per thousand |
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milligram/Liter |
mg/L |
mcg/mL or parts
per million |
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microgram/Liter |
mcg/L |
ng/mL or parts
per billion |
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gram/100 mL |
g/dL |
Percent wt/vol |
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nanogram/mL |
ng/mL |
Microgram/L |
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Report Terminology
Not Detected-
The substance sought quantitatively did not register, being not different
statistically than an appropriate blank.
Not determined-
Could not test for due to technical problem.
Usual therapeutic range-
Inclusive range for the substance/drug being determined based on two or more
references and/or laboratory experience.
Detection Limit-
The lowest concentration in a given determination which can be reliably and reproducibly reported.
Panels-Cover
small groups of substances related pharmacologically. For panels,
qualitative findings are reported.
Surveys-
Qualitative screens which are more extensive than panels. Some surveys
contain quantitative information.
Profiles-
Cover a group of substances all of which are quantitatively determined.
Comprehensive
Toxicologies-
Extensive searches for specific substances and drug classes.
Parent drug-
The term referring to a substance in its prescribed, unmetabolized form.
Metabolite-
A biotransformation product of the parent drug. Thus once a medication
is administered, a patient may have both parent and metabolite
concentrations of clinical significance.
Peak
Concentration-
In therapeutic drug monitoring where a steady state serum concentration
is not obtained, a "peak" refers to the highest concentration of a substance
that occurs following administration of dosage, like the peak of a wave. The
time after administration for reaching a peak concentration is different for
different medications.
Trough
Concentration-
Like the trough of a wave, this is the lowest concentration of a therapeutic
drug, generally assumed to be such immediately before administration of the
next dosage of a non-steady state medication.
Drug Class-
Certain drugs that are chemically similar may be grouped together and tested
for as a class. For example, benzodiazepines refers to a general class of
drugs, which includes Librium (chlordiazepoxide), Valium (diazepam),
and others. AB-C can test for either a class or a specific agent within a
class.
Toxic
Concentration-
That concentration, usually 3 to 5 times the highest value of the
therapeutic range of a substance, which produces life threatening effects.
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